Evaluation of the beta 2 adrenoceptor agonist/antagonist activity of formoterol and salmeterol.

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Evaluation of the beta 2 adrenoceptor agonist/antagonist activity of formoterol and salmeterol.

BACKGROUND Salmeterol and formoterol have a lower intrinsic activity at beta 2 receptors than isoprenaline in human bronchus in vitro. The aim of the present study was to evaluate in vivo the beta 2 agonist/antagonist activity of salmeterol and formoterol at rest with low endogenous adrenergic tone, on exercise with raised endogenous adrenergic tone, and in the presence of fenoterol, an exogeno...

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ژورنال

عنوان ژورنال: Thorax

سال: 1996

ISSN: 0040-6376

DOI: 10.1136/thx.51.1.54